Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: SIX3 (Q62233)
Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
Gene: SIX3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 17666527
Identification Methods anti bait coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 488
Mm

1 333
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024