HitPredict

Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: SIN3A (Q60520)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.704

The method score is based on:

Property Details
Experiments 18454139, 16109738, 20404188, 19424149, 24240174
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 488
Mm

1 1274
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Sp
+ Ce
+ Ce
+ At
+ At
+ Dm
+ Sc
+ Hs
+ Dm
+ Hs
+ Sp
+ Sc
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024