HitPredict

Interactor 1: Q8IPP3 (Q8IPP3)
Canoe, isoform D
Gene: cno

Interactor 2: Q9VHK4 (Q9VHK4)
Polychaetoid, isoform B
Gene: pyd

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	9858699
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0005912 - adherens junction GO:0007391 - dorsal closure GO:0050839 - cell adhesion molecule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1817 Dm			1 1371
+	Hs
		936310 AFAD_HUMAN (1-1302): 0: 713: 39.12		ZO1_HUMAN (1-1280): 0: 653: 29.31
+	Dm
		1173203 Q24279_DROME (660-1289): 1.81e-100: 361: 74.13		Q7K4E2_DROME (3-803): 0: 628: 97.50
+	Hs
		936313 AFAD_HUMAN (1-1302): 0: 713: 39.12		PTN13_HUMAN (189-632): 2.09e-25: 117: 12.47
+	Hs
		936314 AFAD_HUMAN (1-1302): 0: 713: 39.12		DLG1_HUMAN (6-122): 3.99e-15: 82.9: 30.25
+	Hs
		936475 AFAD_HUMAN (1-1302): 0: 713: 39.12		ZO2_HUMAN (379-622): 2.79e-12: 73.7: 18.25
+	Hs
		936394 AFAD_HUMAN (1-1302): 0: 713: 39.12		DLG5_HUMAN (15-159): 1.79e-11: 71.4: 26.85
+	Hs
		1090189 KI13B_HUMAN (247-705): 2.64e-56: 218: 15.40		PTN13_HUMAN (189-632): 2.09e-25: 117: 12.47
+	Mm
		98001 E9Q4K7_MOUSE (249-705): 4.96e-58: 224: 15.03		DLG4_MOUSE (6-299): 3.77e-23: 108: 14.85
+	Hs
		1006107 KI13B_HUMAN (247-705): 2.64e-56: 218: 15.40		DLG4_HUMAN (6-299): 5.9e-23: 107: 14.85
+	Hs
		1091574 KI13B_HUMAN (247-705): 2.64e-56: 218: 15.40		DLG1_HUMAN (6-122): 3.99e-15: 82.9: 30.25
+	Hs
		1152416 DLG2_HUMAN (867-1272): 4.16e-31: 135: 14.85		DLG3_HUMAN (10-307): 2.96e-24: 112: 18.51
+	Hs
		1006071 DLG2_HUMAN (867-1272): 4.16e-31: 135: 14.85		DLG4_HUMAN (6-299): 5.9e-23: 107: 14.85
+	Mm
		1223689 DLG2_MOUSE (849-1272): 1.7e-30: 133: 14.55		DLG4_MOUSE (6-299): 3.77e-23: 108: 14.85
+	Mm
		1223569 NEB2_MOUSE (995-1109): 2.55e-30: 132: 37.82		DLG4_MOUSE (6-299): 3.77e-23: 108: 14.85
+	Hs
		1091503 DLG2_HUMAN (867-1272): 4.16e-31: 135: 14.85		DLG1_HUMAN (6-122): 3.99e-15: 82.9: 30.25
+	Mm
		1247106 NEB2_MOUSE (995-1109): 2.55e-30: 132: 37.82		DLG1_MOUSE (6-122): 2.24e-14: 80.6: 29.41
+	Rn
		1224262 DLG2_RAT (849-1272): 2.98e-30: 132: 15.18		DLG1_RAT (6-122): 3.14e-14: 80.2: 29.41
+	Hs
		1402531 NEB2_HUMAN (995-1109): 2.46e-30: 132: 37.82		ZO2_HUMAN (379-622): 2.79e-12: 73.7: 18.25
+	Mm
		999796 DLG2_MOUSE (849-1272): 1.7e-30: 133: 14.55		DLG3_MOUSE (295-476): 2.37e-11: 70.6: 16.75
+	Mm
		999788 NEB2_MOUSE (995-1109): 2.55e-30: 132: 37.82		DLG3_MOUSE (295-476): 2.37e-11: 70.6: 16.75