Interactor 1: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1
Interactor 2: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31839598 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Anticodon_3~Anticodon_3, Anticodon_3~tRNA-synt_1g, GST_C~GST_C, GST_C~GST_N_5, tRNA-synt_1g~tRNA-synt_1g |
| Common GO terms | GO:0000049 - tRNA binding GO:0004825 - methionine-tRNA ligase activity GO:0005524 - ATP binding GO:0005730 - nucleolus GO:0005737 - cytoplasm and 10 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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| + | Mm |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
