HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: ZN281 (Q9Y2X9)
Zinc finger protein 281 (GC-box-binding zinc finger protein 1) (Transcription factor ZBP-99) (Zinc finger DNA-binding protein 99)
Gene: ZNF281

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 895
+	Hs
		941159 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN808_HUMAN (29-645): 0: 602: 13.84
+	Hs
		941352 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN184_HUMAN (314-853): 0: 570: 13.00
+	Hs
		67423 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN850_HUMAN (15-576): 0: 558: 14.53
+	Hs
		941023 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN658_HUMAN (53-869): 2.12e-160: 498: 9.48
+	Hs
		941165 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN283_HUMAN (169-548): 3.92e-115: 368: 16.75
+	Hs
		941453 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN160_HUMAN (499-869): 9.9e-113: 366: 9.04
+	Hs
		941201 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN420_HUMAN (570-853): 1.73e-82: 281: 11.42
+	Hs
		941120 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN227_HUMAN (15-287): 1.75e-71: 253: 12.98
+	Hs
		563297 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZNF16_HUMAN (565-875): 9.94e-61: 221: 8.63
+	Hs
		941407 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN436_HUMAN (121-340): 1.64e-54: 198: 21.98
+	Hs
		941171 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZFP62_HUMAN (15-160): 1.32e-24: 112: 10.96
+	Hs
		941188 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN740_HUMAN (259-367): 2.91e-27: 111: 51.38
+	Hs
		941306 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN845_HUMAN (648-875): 6.09e-16: 84.7: 6.64
+	Hs
		275733 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN189_HUMAN (258-365): 3.12e-14: 79: 29.73
+	Hs
		941545 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZNF70_HUMAN (258-343): 4.87e-12: 71.2: 41.86
+	Hs
		941025 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN468_HUMAN (259-364): 1.1e-11: 70.5: 35.85
+	Hs
		563763 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZNF28_HUMAN (282-364): 5.32e-09: 62: 36.15