Protein: TCF7
Transcription factor 7 (TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) (TCF-1)

Gene: TCF7
Organism: Homo sapiens
Interactions: 30
UniProt ID: P36402

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 - DNA-binding transcription repressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

764490

CTNB1
Catenin beta-1

9

20

Small-scale

0.962

High

783079

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

Small-scale

0.578

High

162798

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

5

Small-scale

0.561

High

273982

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.541

High

65299

RFOX3
RNA binding protein fox-1 homolog 3

1

8

High-throughput

0.536

High

542357

TOP2A
DNA topoisomerase 2-alpha

1

3

High-throughput

0.536

High

783073

BC11B
B-cell lymphoma/leukemia 11B

1

5

High-throughput

0.536

High

783065

AF1Q
Protein AF1q

1

1

Small-scale

0.506

High

783070

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

4

Small-scale

0.501

High

389100

FINC
Fibronectin

1

1

High-throughput

0.489

High

403875

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

606338

CEBPB
CCAAT/enhancer-binding protein beta

1

14

High-throughput

0.479

High

612903

EGR1
Early growth response protein 1

1

16

Small-scale

0.479

High

629606

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

731020

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

764261

CTNA1
Catenin alpha-1

1

2

Small-scale

0.479

High

783064

CTBP2
C-terminal-binding protein 2

1

12

High-throughput

0.479

High

783066

CUL4A
Cullin-4A

1

15

High-throughput

0.479

High

783067

RUNX3
Runt-related transcription factor 3

1

7

Small-scale

0.479

High

783069

DAZP2
DAZ-associated protein 2

1

5

Small-scale

0.479

High

783071

HIF1A
Hypoxia-inducible factor 1-alpha

1

20

Small-scale

0.479

High

783074

VSX1
Visual system homeobox 1

1

20

High-throughput

0.479

High

783075

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

783076

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

3

Small-scale

0.479

High

783077

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

12

Small-scale

0.479

High

783068

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

208471

PJA2
E3 ubiquitin-protein ligase Praja-2

1

3

Small-scale

0.437

High

539962

BCR
Breakpoint cluster region protein

1

3

Small-scale

0.437

High

783072

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.407

High

783078

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025