HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 746
+	Hs
		1080275 TCPH_HUMAN (4-532): 0: 591: 34.08		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945919 TCPH_MOUSE (4-534): 0: 599: 33.77		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		826679 TCPG_HUMAN (3-532): 0: 561: 28.33		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		573276 TCPA_HUMAN (5-533): 0: 541: 34.30		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		821226 TCPE_HUMAN (1-528): 0: 541: 32.29		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945989 TCPG_MOUSE (3-532): 0: 563: 28.52		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Sc
		755767 TCPB_YEAST (9-532): 0: 566: 65.71		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Sc
		755775 TCPH_YEAST (1-532): 0: 559: 33.09		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		1296406 TCPH_HUMAN (4-532): 0: 591: 34.08		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1306682 TCPH_HUMAN (4-532): 0: 591: 34.08		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203775 TCPH_HUMAN (4-532): 0: 591: 34.08		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		203660 TCPB_HUMAN (1-535): 0: 586: 100.00		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		826825 TCPG_HUMAN (3-532): 0: 561: 28.33		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		826887 TCPG_HUMAN (3-532): 0: 561: 28.33		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203640 TCPG_HUMAN (3-532): 0: 561: 28.33		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		573423 TCPA_HUMAN (5-533): 0: 541: 34.30		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		573479 TCPA_HUMAN (5-533): 0: 541: 34.30		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		821409 TCPE_HUMAN (1-528): 0: 541: 32.29		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203623 TCPA_HUMAN (5-533): 0: 541: 34.30		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		203639 TCPE_HUMAN (1-528): 0: 541: 32.29		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90