HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: LRRK1 (Q38SD2)
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)
Gene: LRRK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32707033, 20697350
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 2015
+	Hs
		1105482 TCPH_HUMAN (4-532): 0: 591: 34.08		LRRK1_HUMAN (1-2015): 0: 1859: 99.60
+	Hs
		826684 TCPG_HUMAN (3-532): 0: 561: 28.33		LRRK1_HUMAN (1-2015): 0: 1859: 99.60
+	Hs
		573283 TCPA_HUMAN (5-533): 0: 541: 34.30		LRRK1_HUMAN (1-2015): 0: 1859: 99.60
+	Hs
		821234 TCPE_HUMAN (1-528): 0: 541: 32.29		LRRK1_HUMAN (1-2015): 0: 1859: 99.60
+	Hs
		1121648 Q53HV2_HUMAN (4-532): 0: 589: 34.08		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		943272 TCPB_HUMAN (1-535): 0: 586: 100.00		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		826696 TCPG_HUMAN (3-532): 0: 561: 28.33		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		1130804 V9HW37_HUMAN (1-528): 0: 541: 32.29		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		573297 TCPA_HUMAN (5-533): 0: 541: 34.30		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65
+	Hs
		821249 TCPE_HUMAN (1-528): 0: 541: 32.29		LRRK2_HUMAN (47-285): 1.02e-20: 102: 11.65