HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26972000
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 721
+	Hs
		1085489 TCPH_HUMAN (4-532): 0: 591: 34.08		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		826682 TCPG_HUMAN (3-532): 0: 561: 28.33		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		573281 TCPA_HUMAN (5-533): 0: 541: 34.30		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		821229 TCPE_HUMAN (1-528): 0: 541: 32.29		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		678579 TCPH_HUMAN (4-532): 0: 591: 34.08		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		625579 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		625349 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Rn
		600431 TCPB_RAT (1-535): 0: 584: 97.76		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		678541 TCPG_HUMAN (3-532): 0: 561: 28.33		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Rn
		600467 TCPG_RAT (3-532): 0: 565: 28.89		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		573140 TCPA_HUMAN (5-533): 0: 541: 34.30		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		625228 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		678540 TCPE_HUMAN (1-528): 0: 541: 32.29		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Rn
		600455 TCPE_RAT (8-524): 0: 554: 33.02		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Sc
		691072 TCPH_YEAST (1-532): 0: 559: 33.09		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Hs
		573132 TCPA_HUMAN (5-533): 0: 541: 34.30		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		625220 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Sc
		539352 TCPB_YEAST (9-532): 0: 566: 65.71		KSS1_YEAST (14-338): 3.59e-121: 368: 37.76
+	Sc
		539365 TCPH_YEAST (1-532): 0: 559: 33.09		KSS1_YEAST (14-338): 3.59e-121: 368: 37.76
+	Sc
		691051 TCPG_YEAST (5-528): 0: 537: 28.33		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78