HitPredict

Interactor 1: OLR1 (P78380)
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (C-type lectin domain family 8 member A) (Lectin-like oxidized LDL receptor 1) (LOX-1) (Lectin-like oxLDL receptor 1) (hLOX-1) (Lectin-type oxidized LDL receptor 1) [Cleaved into: Oxidized low-density lipoprotein receptor 1, soluble form]
Gene: OLR1

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 273 Hs			1 258
+	Hs
		436251 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		943570 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66
+	Hs
		892312 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		943565 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		925183 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		900369 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545314 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		893892 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564474 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		943573 OLR1_HUMAN (1-273): 4.47e-82: 249: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26
+	Hs
		1183535 CLC7A_HUMAN (4-270): 1.63e-52: 173: 29.48		RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00
+	Hs
		1328158 CLC4E_HUMAN (117-266): 9.82e-41: 141: 24.36		RAB1B_HUMAN (42-256): 2.47e-79: 239: 22.69
+	Hs
		1263903 CLC4D_HUMAN (116-265): 6.12e-40: 139: 21.43		RAB1B_HUMAN (42-256): 2.47e-79: 239: 22.69
+	Hs
		914455 CLC4E_HUMAN (117-266): 9.82e-41: 141: 24.36		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		914252 CLC4D_HUMAN (116-265): 6.12e-40: 139: 21.43		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		900410 CD69_HUMAN (142-266): 2.89e-33: 121: 25.60		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		925694 MRC2_HUMAN (156-264): 3.69e-12: 68.3: 20.72		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		914427 MRC2_HUMAN (156-264): 3.69e-12: 68.3: 20.72		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		901008 MRC2_HUMAN (156-264): 3.69e-12: 68.3: 20.72		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545677 MRC2_HUMAN (156-264): 3.69e-12: 68.3: 20.72		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52