Protein: FOXP3
Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form]

Gene: FOXP3
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q9BZS1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

190090

FOXP2
Forkhead box protein P2

3

17

High-throughput

0.871

High

1308722

FOXP4
Forkhead box protein P4

3

18

High-throughput

0.871

High

1420198

FOXP1
Forkhead box protein P1

3

16

High-throughput

0.871

High

340935

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

3

20

Small-scale

0.827

High

1045737

TF65
Transcription factor p65

2

17

Small-scale

0.754

High

1372073

RBPMS
RNA-binding protein with multiple splicing

4

2

High-throughput

0.710

High

938027

FOXA3
Hepatocyte nuclear factor 3-gamma

1

18

High-throughput

0.691

High

1244937

FOXR1
Forkhead box protein R1

1

19

High-throughput

0.691

High

1420209

CHIP
E3 ubiquitin-protein ligase CHIP

2

3

Small-scale

0.646

High

1067690

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.624

High

1048993

REL
Proto-oncogene c-Rel

1

17

Small-scale

0.618

High

1017744

PR20A
Proline-rich protein 20A

4

3

High-throughput

0.616

High

921059

FOSB
Protein FosB

2

5

High-throughput

0.606

High

1186702

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.606

High

1307094

KRA81
Keratin-associated protein 8-1

2

1

High-throughput

0.606

High

1419108

KRA33
Keratin-associated protein 3-3

2

2

High-throughput

0.606

High

1420202

SMYD2
N-lysine methyltransferase SMYD2

2

0

High-throughput

0.602

High

1371278

KAT5
Histone acetyltransferase KAT5

2

6

Small-scale

0.601

High

1017603

PR20E
Proline-rich protein 20E

3

3

High-throughput

0.588

High

1029932

RUNX1
Runt-related transcription factor 1

1

5

Small-scale

0.578

High

1420195

FOXP3
Forkhead box protein P3

1

17

High-throughput

0.575

High

1420197

IKZF4
Zinc finger protein Eos

1

10

Small-scale

0.573

High

1420204

NLK
Serine/threonine-protein kinase NLK

1

4

Small-scale

0.561

High

1028380

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.537

High

229074

AKAP8
A-kinase anchor protein 8

1

6

High-throughput

0.536

High

334092

SMC2
Structural maintenance of chromosomes protein 2

1

13

High-throughput

0.536

High

390163

ALBU
Albumin

1

5

High-throughput

0.536

High

407892

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

451568

CENPB
Major centromere autoantigen B

1

3

High-throughput

0.536

High

541056

PIM1
Serine/threonine-protein kinase pim-1

1

2

Small-scale

0.536

High

700954

PSB4
Proteasome subunit beta type-4

1

2

High-throughput

0.536

High

718620

CDC27
Cell division cycle protein 27 homolog

1

3

High-throughput

0.536

High

725189

HXC13
Homeobox protein Hox-C13

1

20

High-throughput

0.536

High

814571

FEN1
Flap endonuclease 1

1

3

High-throughput

0.536

High

903018

NOVA1
RNA-binding protein Nova-1

1

14

High-throughput

0.536

High

907570

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.536

High

937335

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

10

High-throughput

0.536

High

945309

NU107
Nuclear pore complex protein Nup107

1

3

High-throughput

0.536

High

1032779

SATB1
DNA-binding protein SATB1

1

20

High-throughput

0.536

High

1036591

SEMG2
Semenogelin-2

1

1

High-throughput

0.536

High

1086309

TFCP2
Alpha-globin transcription factor CP2

1

11

High-throughput

0.536

High

1155734

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

Small-scale

0.536

High

1160990

NRF1
Nuclear respiratory factor 1

1

2

High-throughput

0.536

High

1203606

ZN326
DBIRD complex subunit ZNF326

1

6

High-throughput

0.536

High

1215656

ZBT37
Zinc finger and BTB domain-containing protein 37

1

15

High-throughput

0.536

High

1286791

KAISO
Transcriptional regulator Kaiso

1

3

High-throughput

0.536

High

1295744

HIPK1
Homeodomain-interacting protein kinase 1

1

6

High-throughput

0.536

High

1323148

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.536

High

1335866

ZBT34
Zinc finger and BTB domain-containing protein 34

1

20

High-throughput

0.536

High

1356934

NU133
Nuclear pore complex protein Nup133

1

1

High-throughput

0.536

High

1368102

HDAC2
Histone deacetylase 2

1

19

High-throughput

0.536

High

1384567

NACC2
Nucleus accumbens-associated protein 2

1

20

High-throughput

0.536

High

1393944

FUBP3
Far upstream element-binding protein 3

1

12

High-throughput

0.536

High

1396348

ZFR
Zinc finger RNA-binding protein

1

8

High-throughput

0.536

High

1401281

NACC1
Nucleus accumbens-associated protein 1

1

20

High-throughput

0.536

High

1402245

WRIP1
ATPase WRNIP1

1

3

High-throughput

0.536

High

1420199

ESRP2
Epithelial splicing regulatory protein 2

1

6

High-throughput

0.536

High

1420203

UBIP1
Upstream-binding protein 1

1

11

High-throughput

0.536

High

1420205

CDC23
Cell division cycle protein 23 homolog

1

3

High-throughput

0.536

High

1420206

RALY
RNA-binding protein Raly

1

6

High-throughput

0.536

High

1420210

NOVA2
RNA-binding protein Nova-2

1

14

High-throughput

0.536

High

1420211

SATB2
DNA-binding protein SATB2

1

20

High-throughput

0.536

High

1420212

SMC3
Structural maintenance of chromosomes protein 3

1

14

High-throughput

0.536

High

1356766

HDAC7
Histone deacetylase 7

1

20

Small-scale

0.534

High

1420207

IKZF3
Zinc finger protein Aiolos

1

10

Small-scale

0.534

High

1420208

HDAC9
Histone deacetylase 9

1

20

Small-scale

0.534

High

186268

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.529

High

1420196

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

1

5

Small-scale

0.515

High

700725

PSA5
Proteasome subunit alpha type-5

1

0

High-throughput

0.513

High

1085280

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.513

High

1213145

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.513

High

1420201

ELP3
Elongator complex protein 3

1

0

High-throughput

0.513

High

1353570

ZFP90
Zinc finger protein 90 homolog

1

0

Small-scale

0.506

High

771014

RORA
Nuclear receptor ROR-alpha

1

20

Small-scale

0.506

High

1420200

KAT8
Histone acetyltransferase KAT8

1

6

Small-scale

0.501

High

567070

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

3

High-throughput

0.489

High

485394

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

Small-scale

0.479

High

533971

IRF1
Interferon regulatory factor 1

1

6

Small-scale

0.479

High

662649

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

16

Small-scale

0.479

High

771608

HXD13
Homeobox protein Hox-D13

1

20

High-throughput

0.479

High

902790

RORG
Nuclear receptor ROR-gamma

1

20

Small-scale

0.479

High

967954

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

Small-scale

0.479

High

1110052

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

1154004

SMAD1
Mothers against decapentaplegic homolog 1

1

7

Small-scale

0.479

High

1311602

SUGP2
SURP and G-patch domain-containing protein 2

1

4

High-throughput

0.479

High

1371666

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

Small-scale

0.479

High

1388715

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

7

Small-scale

0.479

High

1017621

PR20C
Proline-rich protein 20C

1

3

High-throughput

0.470

High

1017671

PR20D
Proline-rich protein 20D

1

3

High-throughput

0.470

High

595586

H15
Histone H1.5

1

0

Small-scale

0.458

High

285460

EED
Polycomb protein EED

1

16

Small-scale

0.445

High

537858

HSP7C
Heat shock cognate 71 kDa protein

1

5

Small-scale

0.445

High

1100349

TIF1B
Transcription intermediary factor 1-beta

1

6

Small-scale

0.445

High

1137508

SUZ12
Polycomb protein SUZ12

1

1

Small-scale

0.445

High


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Last updated: 11Aug2025