HitPredict

Interactor 1: H4 (P84040)
Histone H4
Gene: His4

Interactor 2: SMBT (Q9VK33)
Polycomb protein Sfmbt (Scm-like with four MBT domain-containing protein 1) (dSfmbt)
Gene: Sfmbt

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	19494831, 16618800, 24186981
Identification Methods	x-ray crystallography, pull down
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 103 Dm			1 1220
+	Hs
		917704 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL2_HUMAN (535-1058): 0: 623: 43.53
+	Hs
		917155 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		MBTD1_HUMAN (439-1042): 0: 611: 37.56
+	Hs
		918153 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SCML2_HUMAN (518-1202): 0: 579: 18.43
+	Hs
		917753 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL3_HUMAN (236-811): 4.3e-160: 498: 19.42
+	Hs
		918096 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SMBT1_HUMAN (489-1203): 2.08e-105: 355: 19.58
+	Dm
		950403 H4_DROME (1-103): 2.46e-48: 150: 100.00		Q9VB52_DROME (460-874): 9.39e-94: 332: 24.24
+	Hs
		917562 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		PHC2_HUMAN (970-1201): 1.74e-43: 173: 17.62
+	Hs
		917467 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SAMD1_HUMAN (1000-1215): 5e-42: 164: 15.42
+	Hs
		917614 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		PHC3_HUMAN (994-1202): 3.35e-32: 138: 18.98
+	Hs
		918192 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL1_HUMAN (512-683): 1.38e-28: 126: 19.32
+	Dm
		950411 H4_DROME (1-103): 2.46e-48: 150: 100.00		SCM_DROME (273-647): 3.33e-14: 79.9: 16.10