HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 172
+	At
		1247085 Q8RWF8_ARATH (11-162): 3.43e-25: 100: 27.39		Q8RWF8_ARATH (3-171): 1.34e-33: 123: 31.36
+	Hs
		951924 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		516466 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		516478 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		266904 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		1084363 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		RMXL1_HUMAN (2-86): 1.01e-18: 83.6: 62.35
+	Hs
		474017 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PAB4L_HUMAN (7-84): 2.44e-20: 88: 32.05
+	Hs
		925048 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Mm
		857340 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		TIA1_MOUSE (2-164): 5.99e-19: 84.1: 18.33
+	Hs
		952076 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RMXL1_HUMAN (2-86): 1.01e-18: 83.6: 62.35
+	Hs
		992876 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		RMXL1_HUMAN (2-86): 1.01e-18: 83.6: 62.35
+	Hs
		745125 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		680437 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		TIA1_HUMAN (2-164): 7.27e-18: 81.1: 17.78
+	Hs
		266929 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Mm
		936481 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		TIAR_MOUSE (2-151): 3.03e-16: 76.8: 20.53
+	Hs
		925003 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		925011 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Mm
		925159 SRSF3_MOUSE (1-164): 6.39e-27: 100: 100.00		TRA2B_MOUSE (8-132): 2.95e-15: 73.2: 46.40
+	Mm
		192621 SRSF5_MOUSE (10-112): 1.98e-24: 97: 44.34		TRA2B_MOUSE (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		266958 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40