HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: MET14 (Q9HCE5)
N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14)
Gene: METTL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29507755, 36597993
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 164 Hs			1 456
+	Hs
		1084419 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		992946 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		267078 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1028623 SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1029108 SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44		MET14_HUMAN (1-433): 0: 654: 100.00