HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22453275
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 246
+	Hs
		727874 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		SOX6_HUMAN (49-160): 2.17e-25: 106: 12.82
+	Hs
		935263 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Hs
		952640 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Hs
		175769 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HMGB3_HUMAN (46-136): 1.77e-17: 79.8: 21.98
+	Hs
		175771 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HMGB3_HUMAN (46-136): 1.77e-17: 79.8: 21.98
+	Hs
		643320 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84
+	Hs
		643324 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84
+	Hs
		935035 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HMGB4_HUMAN (46-143): 9.81e-15: 72.1: 17.35
+	Hs
		449665 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Hs
		449674 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Hs
		643360 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84
+	Hs
		449756 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Mm
		952739 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		SSRP1_MOUSE (118-219): 1.25e-11: 66: 26.42
+	Hs
		567673 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		UBF1_HUMAN (51-214): 4.22e-11: 64.4: 20.46
+	Hs
		567675 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		UBF1_HUMAN (51-214): 4.22e-11: 64.4: 20.46
+	Hs
		643358 H3C_HUMAN (1-136): 1.99e-56: 173: 95.59		HMGB2_HUMAN (48-142): 4.13e-15: 73.3: 16.84
+	Hs
		567719 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		UBF1_HUMAN (51-214): 4.22e-11: 64.4: 20.46
+	Sc
		902006 H3_YEAST (1-136): 3.62e-54: 168: 90.44		ABF2_YEAST (153-223): 2.99e-09: 56.7: 30.67
+	Hs
		449604 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Hs
		567659 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		UBF1_HUMAN (51-214): 4.22e-11: 64.4: 20.46