HitPredict

Interactor 1: IL2 (P60568)
Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
Gene: IL2

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	7623820, 1508203
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 153 Hs			1 619
+	Mm
		408207 IL2_MOUSE (1-151): 6.78e-71: 212: 57.23		TF65_MOUSE (2-576): 2e-167: 490: 38.89
+	Hs
		952406 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		TF65_HUMAN (2-576): 4.76e-158: 466: 37.89
+	Hs
		952411 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC3_HUMAN (1-610): 1.35e-128: 406: 15.35
+	Hs
		952412 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC2_HUMAN (1-504): 1.27e-88: 296: 14.84
+	Hs
		340861 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC1_HUMAN (1-486): 1.56e-76: 264: 15.32
+	Mm
		408208 IL2_MOUSE (1-151): 6.78e-71: 212: 57.23		NFAC2_MOUSE (1-485): 8.56e-85: 286: 15.34