Protein: FUS3
Mitogen-activated protein kinase FUS3 (MAP kinase FUS3) (EC 2.7.11.24)

Gene: FUS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 145
UniProt ID: P16892

Gene Ontology (top 5):
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562696

STE5
Protein STE5

23

1

Small-scale

0.990

High

420010

STE7
Serine/threonine-protein kinase STE7

21

20

Small-scale

0.990

High

562684

STE11
Serine/threonine-protein kinase STE11

7

16

Small-scale

0.953

High

562708

MSG5
Tyrosine-protein phosphatase MSG5

5

20

Small-scale

0.922

High

562672

FUS3
Mitogen-activated protein kinase FUS3

4

19

Small-scale

0.898

High

562722

PTP3
Tyrosine-protein phosphatase 3

2

19

Small-scale

0.838

High

562709

RCK1
Serine/threonine-protein kinase RCK1

2

20

High-throughput

0.789

High

562751

DIG2
Down-regulator of invasive growth 2

9

1

Small-scale

0.757

High

539296

KSS1
Mitogen-activated protein kinase KSS1

2

17

Small-scale

0.743

High

562749

DIG1
Down-regulator of invasive growth 1

6

1

Small-scale

0.742

High

562673

TEC1
Ty transcription activator TEC1

4

2

Small-scale

0.700

High

423656

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.691

High

562704

BOB1
Protein BOB1

1

8

High-throughput

0.691

High

562745

CDC14
Tyrosine-protein phosphatase CDC14

1

20

High-throughput

0.691

High

440228

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

3

3

Small-scale

0.670

High

562681

FAR1
Cyclin-dependent kinase inhibitor FAR1

4

0

Small-scale

0.666

High

529989

STE12
Protein STE12

3

2

Small-scale

0.664

High

514954

RNA1
Ran GTPase-activating protein 1

1

5

High-throughput

0.647

High

516789

SST2
Protein SST2

1

1

Small-scale

0.647

High

543134

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.647

High

562678

FKBP
FK506-binding protein 1

1

6

High-throughput

0.647

High

562682

KCC2
Calcium/calmodulin-dependent protein kinase II

1

20

High-throughput

0.647

High

562742

JJJ1
J protein JJJ1

1

7

High-throughput

0.647

High

562777

ARP8
Actin-like protein ARP8

1

8

High-throughput

0.647

High

419793

SNF1
Carbon catabolite-derepressing protein kinase

1

2

Small-scale

0.621

High

562765

RGC1
Regulator of the glycerol channel 1

2

5

High-throughput

0.619

High

562721

BOI2
Protein BOI2

1

10

High-throughput

0.618

High

562746

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

7

Small-scale

0.602

High

562689

TF2B
Transcription initiation factor IIB

2

9

High-throughput

0.595

High

554542

HSP26
Heat shock protein 26

2

3

High-throughput

0.588

High

562677

HSP60
Heat shock protein 60, mitochondrial

2

9

High-throughput

0.588

High

562776

HSP42
Heat shock protein 42

2

3

High-throughput

0.588

High

389680

CDC25
Cell division control protein 25

1

3

Small-scale

0.578

High

562718

MPT5
Suppressor protein MPT5

1

1

Small-scale

0.573

High

524146

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.569

High

562771

ALR1
Magnesium transporter ALR1

2

1

High-throughput

0.565

High

562715

KEL1
Kelch repeat-containing protein 1

1

5

Small-scale

0.561

High

562719

RV167
Reduced viability upon starvation protein 167

1

2

Small-scale

0.536

High

562692

XPO1
Exportin-1

1

3

High-throughput

0.536

High

562698

BCK2
Protein BCK2

1

1

High-throughput

0.536

High

562710

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.536

High

562733

NET1
Nucleolar protein NET1

1

1

High-throughput

0.536

High

562735

ASK10
Activator of SKN7 protein 10

1

5

High-throughput

0.536

High

562741

VPS75
Vacuolar protein sorting-associated protein 75

1

4

High-throughput

0.515

High

562752

YM8V
Uncharacterized protein YMR295C

1

0

High-throughput

0.513

High

562753

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.513

High

343268

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

5

High-throughput

0.501

High

356228

H4
Histone H4

1

2

Small-scale

0.501

High

392044

H2A1
Histone H2A.1

1

3

High-throughput

0.501

High

439962

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.501

High

442924

LEUR
Regulatory protein LEU3

1

3

High-throughput

0.501

High

472559

YH11A
Transposon Ty1-H Gag polyprotein

1

9

High-throughput

0.501

High

482550

YA11A
Transposon Ty1-A Gag polyprotein

1

11

High-throughput

0.501

High

482584

YP13A
Transposon Ty1-PR2 Gag polyprotein

1

10

High-throughput

0.501

High

482610

YE11A
Transposon Ty1-ER1 Gag polyprotein

1

10

High-throughput

0.501

High

549021

TRM1
tRNA

1

3

High-throughput

0.501

High

562676

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.501

High

562685

MCM3
DNA replication licensing factor MCM3

1

11

High-throughput

0.501

High

562686

IF2M
Translation initiation factor IF-2, mitochondrial

1

4

High-throughput

0.501

High

562687

PTP1
Tyrosine-protein phosphatase 1

1

14

Small-scale

0.501

High

562691

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.501

High

562693

RML2
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.501

High

562699

YBF5
Deoxyribonuclease Tat-D

1

1

High-throughput

0.501

High

562702

EF1G2
Elongation factor 1-gamma 2

1

8

High-throughput

0.501

High

562712

APM2
Adaptin medium chain homolog APM2

1

2

High-throughput

0.501

High

562713

TOM71
Protein TOM71

1

3

High-throughput

0.501

High

562720

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

4

High-throughput

0.501

High

562728

ELP2
Elongator complex protein 2

1

6

High-throughput

0.501

High

562729

BUD27
Bud site selection protein 27

1

1

High-throughput

0.501

High

562738

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.501

High

562743

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.501

High

562747

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

2

High-throughput

0.501

High

562759

DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.501

High

562760

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

8

High-throughput

0.501

High

562767

RGA2
Rho-type GTPase-activating protein 2

1

8

Small-scale

0.501

High

562769

BDF2
Bromodomain-containing factor 2

1

11

High-throughput

0.501

High

562773

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

11

High-throughput

0.501

High

562774

SAS10
Something about silencing protein 10

1

1

High-throughput

0.501

High

562778

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

9

High-throughput

0.501

High

562779

YD21A
Transposon Ty2-DR1 Gag polyprotein

1

10

High-throughput

0.501

High

562780

YN12A
Transposon Ty1-NL2 Gag polyprotein

1

11

High-throughput

0.501

High

562782

YP14A
Transposon Ty1-PR3 Gag polyprotein

1

10

High-throughput

0.501

High

562783

YO11A
Transposon Ty1-OL Gag polyprotein

1

10

High-throughput

0.501

High

562675

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.480

High

562688

FUN19
SWIRM domain-containing protein FUN19

1

0

High-throughput

0.480

High

562695

TIM12
Mitochondrial import inner membrane translocase subunit TIM12

1

0

High-throughput

0.480

High

562700

PTH2
Peptidyl-tRNA hydrolase 2

1

0

High-throughput

0.480

High

562714

YHT1
PH domain-containing protein YHR131C

1

0

High-throughput

0.480

High

562717

LYS9
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]

1

0

High-throughput

0.480

High

562726

BNI1
Protein BNI1

1

0

Small-scale

0.480

High

562734

DENR
Translation machinery-associated protein 22

1

0

High-throughput

0.480

High

562736

GYP3
GTPase-activating protein GYP3

1

0

High-throughput

0.480

High

562737

YG51
Uncharacterized protein YGR237C

1

0

High-throughput

0.480

High

562739

YGI2
Uncharacterized protein YGL082W

1

0

High-throughput

0.480

High

562744

EAF7
Chromatin modification-related protein EAF7

1

0

High-throughput

0.480

High

562748

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.480

High

562754

GIR2
Protein GIR2

1

0

High-throughput

0.480

High

562755

ENT5
Epsin-5

1

0

High-throughput

0.480

High

562756

NUP53
Nucleoporin NUP53

1

0

Small-scale

0.480

High

562758

LRS4
Monopolin complex subunit LRS4

1

0

High-throughput

0.480

High

562761

HEL2
E3 ubiquitin-protein ligase HEL2

1

0

High-throughput

0.480

High

562763

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.480

High

562768

LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

1

0

High-throughput

0.480

High

562770

CMS1
Protein CMS1

1

0

High-throughput

0.480

High

562772

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.480

High

562781

PAR32
Protein PAR32

1

0

High-throughput

0.480

High

334429

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

5

High-throughput

0.479

High

410891

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

500297

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

2

Small-scale

0.479

High

562680

PSA7
Probable proteasome subunit alpha type-7

1

4

High-throughput

0.479

High

562683

SPA2
Protein SPA2

1

8

Small-scale

0.479

High

562690

BEM1
Bud emergence protein 1

1

2

Small-scale

0.479

High

562697

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

562727

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.479

High

562730

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.479

High

426360

PMM
Phosphomannomutase

1

0

High-throughput

0.458

High

562757

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

562766

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

381678

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

2

High-throughput

0.457

High

382929

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.457

High

562679

ACO1
Acyl-CoA desaturase 1

1

1

High-throughput

0.457

High

562701

MNR2
Manganese resistance protein MNR2

1

1

High-throughput

0.457

High

562703

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

2

High-throughput

0.457

High

562711

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

6

High-throughput

0.457

High

562723

UTP7
U3 small nucleolar RNA-associated protein 7

1

3

High-throughput

0.457

High

514610

FUS1
Nuclear fusion protein FUS1

1

1

Small-scale

0.457

High

562674

GBB
Guanine nucleotide-binding protein subunit beta

1

8

Small-scale

0.457

High

562716

MTG2
GTPase MTG2, mitochondrial

1

6

High-throughput

0.457

High

490246

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

493122

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

510165

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

562724

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

562775

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.445

High

562750

SDC1
COMPASS component SDC1

1

0

High-throughput

0.438

High

562762

FUS2
Nuclear fusion protein FUS2

1

0

Small-scale

0.438

High

562725

CSS1
Secreted protein CSS1

1

4

High-throughput

0.417

High

562694

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

562706

YB9F
Uncharacterized protein YBR259W

1

0

High-throughput

0.261

Low

562707

YM8C
Uncharacterized deoxyribonuclease YMR262W

1

0

High-throughput

0.261

Low

562731

OSW7
Outer spore wall protein 7

1

0

High-throughput

0.261

Low

562732

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.261

Low

562740

ARE2
Sterol O-acyltransferase 2

1

0

High-throughput

0.261

Low

562764

CST9
Chromosome stability protein 9

1

0

High-throughput

0.261

Low

562705

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024