HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 1726
+	Hs
		934915 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SPT6H_HUMAN (1-1726): 0: 1802: 100.00
+	Dm
		356126 H3_DROME (1-136): 5.32e-59: 180: 97.06		SPT6H_DROME (55-1695): 0: 1485: 46.33
+	Sc
		619160 H3_YEAST (1-136): 3.62e-54: 168: 90.44		SPT6_YEAST (15-1512): 0: 812: 22.21
+	Sc
		619137 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		SPT6_YEAST (15-1512): 0: 812: 22.21
+	Hs
		934981 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SRBD1_HUMAN (218-1212): 0: 597: 16.76
+	Hs
		952468 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SRBD1_HUMAN (218-1212): 0: 597: 16.76
+	Hs
		828299 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		SRBD1_HUMAN (218-1212): 0: 597: 16.76
+	Hs
		935030 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		LEO1_HUMAN (1-345): 1.27e-13: 78.1: 13.68
+	Pf
		86806 C6KSV0_PLAF7 (1-136): 1.57e-57: 176: 90.44		Q8IIS9_PLAF7 (2-319): 8.55e-09: 63.1: 11.01
+	Hs
		828318 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		LEO1_HUMAN (1-345): 1.27e-13: 78.1: 13.68