HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: SUV92 (Q9H5I1)
Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Lysine N-methyltransferase 1B) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
Gene: SUV39H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 410
+	Hs
		935237 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV92_HUMAN (1-410): 6.39e-159: 455: 100.00
+	Hs
		203659 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV91_HUMAN (6-409): 4.93e-141: 410: 56.97
+	Hs
		203664 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SUV91_HUMAN (6-409): 4.93e-141: 410: 56.97
+	Hs
		935251 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT1_HUMAN (81-406): 4.58e-81: 272: 30.66
+	Hs
		952633 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		EHMT1_HUMAN (81-406): 4.58e-81: 272: 30.66
+	Mm
		952777 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		EHMT2_MOUSE (85-406): 2.2e-76: 259: 30.12
+	Hs
		935126 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT2_HUMAN (85-406): 3.51e-75: 255: 30.12
+	Hs
		952553 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		EHMT2_HUMAN (85-406): 3.51e-75: 255: 30.12
+	Hs
		1086279 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		EHMT2_HUMAN (85-406): 3.51e-75: 255: 30.12
+	Hs
		935276 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ASH1L_HUMAN (79-409): 4.58e-72: 247: 20.62
+	Hs
		952649 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		ASH1L_HUMAN (79-409): 4.58e-72: 247: 20.62
+	Hs
		935204 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SETD2_HUMAN (79-409): 1.32e-70: 243: 20.87
+	Hs
		1086306 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		SETD2_HUMAN (79-409): 1.32e-70: 243: 20.87
+	At
		886462 H33_ARATH (1-136): 3.83e-60: 183: 95.59		SUVH4_ARATH (89-409): 2.36e-69: 232: 25.71
+	Hs
		935129 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD1_HUMAN (133-409): 3.82e-64: 224: 27.40
+	Hs
		952555 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NSD1_HUMAN (133-409): 3.82e-64: 224: 27.40
+	Hs
		1086280 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		NSD1_HUMAN (133-409): 3.82e-64: 224: 27.40
+	Hs
		935205 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD3_HUMAN (112-409): 1.48e-62: 220: 25.50
+	Hs
		952607 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NSD3_HUMAN (112-409): 1.48e-62: 220: 25.50
+	Hs
		1086307 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		NSD3_HUMAN (112-409): 1.48e-62: 220: 25.50