HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ARP8 (Q9H981)
Actin-related protein 8 (hArp8) (INO80 complex subunit N)
Gene: ACTR8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0045893 - positive regulation of DNA-templated transcription and 1 others more... GO:0051726 - regulation of cell cycle
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 624
+	Hs
		1200979 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTBL_HUMAN (136-468): 4.1e-62: 212: 16.91
+	Hs
		952905 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTB_HUMAN (401-620): 3.25e-54: 191: 16.29
+	Hs
		993220 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTG_HUMAN (401-620): 3.25e-54: 191: 16.29
+	Hs
		952875 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTB_HUMAN (401-620): 3.25e-54: 191: 16.29
+	Hs
		993208 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTG_HUMAN (401-620): 3.25e-54: 191: 16.29
+	Hs
		977731 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTA_HUMAN (401-620): 8.81e-54: 189: 16.29
+	Hs
		995650 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTC_HUMAN (401-620): 8.81e-54: 189: 16.29
+	Hs
		996478 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTS_HUMAN (401-620): 1.92e-53: 189: 16.29
+	Hs
		977717 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTA_HUMAN (401-620): 8.81e-54: 189: 16.29
+	Hs
		995631 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTC_HUMAN (401-620): 8.81e-54: 189: 16.29
+	Hs
		996469 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTS_HUMAN (401-620): 1.92e-53: 189: 16.29
+	Hs
		993427 POTEE_HUMAN (1-375): 0: 736: 92.00		ACTH_HUMAN (401-620): 6.04e-53: 187: 16.29
+	Hs
		993424 ACTBL_HUMAN (2-375): 0: 735: 91.71		ACTH_HUMAN (401-620): 6.04e-53: 187: 16.29
+	Hs
		506964 POTEE_HUMAN (1-375): 0: 736: 92.00		POTEI_HUMAN (477-620): 8.42e-48: 182: 20.69
+	Hs
		507033 POTEE_HUMAN (1-375): 0: 736: 92.00		POTEJ_HUMAN (477-620): 7.34e-48: 182: 20.69
+	Hs
		62958 ACTBL_HUMAN (2-375): 0: 735: 91.71		POTEF_HUMAN (477-620): 7e-48: 183: 20.69
+	Hs
		506957 ACTBL_HUMAN (2-375): 0: 735: 91.71		POTEI_HUMAN (477-620): 8.42e-48: 182: 20.69
+	Hs
		507031 ACTBL_HUMAN (2-375): 0: 735: 91.71		POTEJ_HUMAN (477-620): 7.34e-48: 182: 20.69
+	Hs
		506919 POTEI_HUMAN (1-375): 0: 731: 91.20		POTEJ_HUMAN (477-620): 7.34e-48: 182: 20.69