Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 30890647, 35575683
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005884 - actin filament
GO:0015629 - actin cytoskeleton
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 377
Hs

1 376
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Sp
+ Zm
+ At
+ Ce
+ Ce
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Oc
+ Gg
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025