HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	38334954, 35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0005524 - ATP binding GO:0005615 - extracellular space GO:0005884 - actin filament GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 376
+	Dm
		387021 ACT4_DROME (1-377): 0: 651: 91.78		ACT5_DROME (1-376): 0: 597: 89.10
+	Dm
		387022 ACT4_DROME (1-377): 0: 651: 91.78		ACT1_DROME (1-376): 0: 597: 90.69
+	Dm
		386963 ACT4_DROME (1-377): 0: 651: 91.78		ACT2_DROME (1-376): 0: 595: 90.16
+	Dm
		387037 ACT4_DROME (1-377): 0: 651: 91.78		ACT3_DROME (1-376): 0: 594: 88.83
+	Dm
		387039 ACT4_DROME (1-377): 0: 651: 91.78		ACT6_DROME (1-376): 0: 594: 88.83
+	Sp
		534526 ACT_SCHPO (4-377): 0: 647: 89.04		ACT_SCHPO (3-376): 0: 586: 85.29
+	Ce
		534393 ACT2_CAEEL (1-377): 0: 608: 94.16		ACT2_CAEEL (1-376): 0: 599: 90.16
+	Ce
		534394 ACT2_CAEEL (1-377): 0: 608: 94.16		ACT4_CAEEL (1-376): 0: 599: 90.16
+	Ce
		515951 ACT2_CAEEL (1-377): 0: 608: 94.16		ACT3_CAEEL (1-376): 0: 598: 90.16
+	Ce
		515952 ACT4_CAEEL (1-377): 0: 608: 94.16		ACT3_CAEEL (1-376): 0: 598: 90.16
+	Ce
		515950 ACT3_CAEEL (1-377): 0: 606: 93.90		ACT3_CAEEL (1-376): 0: 598: 90.16
+	At
		920945 ACT11_ARATH (1-377): 0: 621: 87.80		ACT7_ARATH (2-376): 0: 582: 83.73
+	Hs
		952733 ACTS_HUMAN (1-377): 0: 606: 100.00		ACTB_HUMAN (3-376): 0: 595: 91.71
+	Mm
		996569 ACTS_MOUSE (1-377): 0: 606: 100.00		ACTS_MOUSE (2-376): 0: 588: 87.47
+	Oc
		996587 ACTS_RABIT (1-377): 0: 606: 100.00		ACTS_RABIT (2-376): 0: 588: 87.47
+	Gg
		996592 ACTS_CHICK (1-377): 0: 606: 100.00		ACTS_CHICK (2-376): 0: 588: 87.47
+	Hs
		977671 ACTS_HUMAN (1-377): 0: 606: 100.00		ACTA_HUMAN (1-376): 0: 586: 87.80