HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1162
+	Hs
		903177 ACTBL_HUMAN (2-375): 0: 735: 91.71		SMCA2_HUMAN (84-1159): 0: 577: 16.43
+	Hs
		952785 ACTB_HUMAN (1-375): 0: 603: 100.00		CHD3_HUMAN (170-1160): 0: 610: 15.79
+	Hs
		993150 ACTG_HUMAN (1-375): 0: 601: 98.93		CHD3_HUMAN (170-1160): 0: 610: 15.79
+	Hs
		903297 ACTB_HUMAN (1-375): 0: 603: 100.00		SMCA4_HUMAN (113-1159): 0: 600: 17.03
+	Mm
		993092 ACTG_MOUSE (1-375): 0: 601: 98.93		SMCA4_MOUSE (113-1159): 0: 602: 16.93
+	Hs
		995561 ACTC_HUMAN (2-375): 0: 592: 94.12		CHD3_HUMAN (170-1160): 0: 610: 15.79
+	Hs
		903306 ACTG_HUMAN (1-375): 0: 601: 98.93		SMCA4_HUMAN (113-1159): 0: 600: 17.03
+	Dm
		534416 ACT1_DROME (2-375): 0: 598: 98.13		BRM_DROME (134-1162): 0: 600: 15.86
+	Dm
		386972 ACT2_DROME (2-375): 0: 596: 97.59		BRM_DROME (134-1162): 0: 600: 15.86
+	Hs
		903307 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA4_HUMAN (113-1159): 0: 600: 17.03
+	Hs
		903308 ACTS_HUMAN (2-375): 0: 592: 93.58		SMCA4_HUMAN (113-1159): 0: 600: 17.03
+	Mm
		993102 ACTG_MOUSE (1-375): 0: 601: 98.93		SMCA2_MOUSE (118-1159): 0: 588: 16.71
+	Hs
		952823 ACTB_HUMAN (1-375): 0: 603: 100.00		CHD4_HUMAN (173-1160): 1.08e-180: 580: 14.91
+	Xl
		313500 ACTB_XENLA (1-375): 0: 602: 99.47		Q4VQ79_XENLA (132-1159): 1.04e-179: 571: 16.67
+	Hs
		995594 ACTC_HUMAN (2-375): 0: 592: 94.12		CHD4_HUMAN (173-1160): 1.08e-180: 580: 14.91
+	Hs
		903124 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA2_HUMAN (84-1159): 0: 577: 16.43
+	Hs
		243593 ACTC_HUMAN (2-375): 0: 592: 94.12		SMCA5_HUMAN (452-1162): 4.78e-179: 555: 20.17
+	Zm
		13771 A0A1D6FW13_MAIZE (3-375): 0: 588: 89.28		A0A1D6MT91_MAIZE (438-1159): 3.18e-173: 542: 20.11
+	Sp
		206386 ACT_SCHPO (1-375): 0: 592: 90.40		FFT3_SCHPO (548-1148): 4.56e-34: 144: 26.70