HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: ROR2 (Q01974)
Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)
Gene: ROR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0016055 - Wnt signaling pathway
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 943
+	Hs
		988294 RAC1_HUMAN (1-192): 2.11e-85: 251: 92.71		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		580998 RAC2_HUMAN (1-192): 9.15e-82: 242: 88.54		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		1034343 RHOJ_HUMAN (2-190): 2.65e-80: 239: 60.32		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		1015375 RHOG_HUMAN (1-192): 1.04e-78: 234: 69.79		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		955071 CDC42_HUMAN (1-192): 1.05e-77: 231: 68.75		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		961965 RHOA_HUMAN (5-192): 9.22e-77: 229: 55.32		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		466209 RHOC_HUMAN (5-192): 2.47e-74: 223: 54.79		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		601245 RHOQ_HUMAN (4-189): 1.68e-72: 219: 63.49		ROR2_HUMAN (1-943): 0: 841: 100.00
+	Hs
		1101777 RHOJ_HUMAN (2-190): 2.65e-80: 239: 60.32		PTK7_HUMAN (7-746): 1.16e-146: 464: 22.50
+	Hs
		601184 RHOQ_HUMAN (4-189): 1.68e-72: 219: 63.49		UFO_HUMAN (28-837): 9.17e-150: 467: 19.23
+	Hs
		988305 RAC1_HUMAN (1-192): 2.11e-85: 251: 92.71		FAK1_HUMAN (358-850): 2.39e-110: 367: 27.18
+	Hs
		466280 RHOC_HUMAN (5-192): 2.47e-74: 223: 54.79		DDR2_HUMAN (461-751): 3.32e-55: 208: 38.39