HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33545068
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 446
+	Hs
		601324 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MRCKA_HUMAN (82-406): 1.73e-27: 118: 14.33
+	Hs
		1217563 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		MRCKA_HUMAN (82-406): 1.73e-27: 118: 14.33
+	Hs
		988432 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MRCKA_HUMAN (82-406): 1.73e-27: 118: 14.33
+	Hs
		601331 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MRCKG_HUMAN (175-439): 7.04e-18: 88.6: 13.50
+	Hs
		601518 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MRCKB_HUMAN (229-441): 2.81e-12: 71.3: 12.09
+	Hs
		601393 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MY18A_HUMAN (108-352): 6.96e-11: 66.7: 14.44
+	Hs
		270769 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		ROCK2_HUMAN (113-339): 3.11e-10: 64.8: 17.02
+	Hs
		988444 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MRCKG_HUMAN (175-439): 7.04e-18: 88.6: 13.50
+	Hs
		601383 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		DLG5_HUMAN (136-427): 2.79e-09: 61.7: 9.49
+	Hs
		601313 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		GRDN_HUMAN (135-355): 6.22e-09: 60.6: 21.34
+	Hs
		1433601 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		MRCKB_HUMAN (229-441): 2.81e-12: 71.3: 12.09
+	Hs
		270845 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		ROCK2_HUMAN (113-339): 3.11e-10: 64.8: 17.02
+	Hs
		1351390 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		DLG5_HUMAN (136-427): 2.79e-09: 61.7: 9.49
+	Hs
		988860 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MRCKB_HUMAN (229-441): 2.81e-12: 71.3: 12.09
+	Hs
		1191484 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		GRDN_HUMAN (135-355): 6.22e-09: 60.6: 21.34
+	Hs
		988578 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MY18A_HUMAN (108-352): 6.96e-11: 66.7: 14.44
+	Hs
		270795 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		ROCK2_HUMAN (113-339): 3.11e-10: 64.8: 17.02
+	Hs
		988547 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		DLG5_HUMAN (136-427): 2.79e-09: 61.7: 9.49
+	Hs
		988410 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		GRDN_HUMAN (135-355): 6.22e-09: 60.6: 21.34
+	Hs
		772724 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05