HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2157
+	Hs
		962018 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		MYO9B_HUMAN (1-2157): 0: 1573: 100.00
+	Hs
		466239 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		MYO9B_HUMAN (1-2157): 0: 1573: 100.00
+	Hs
		601517 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MYO5A_HUMAN (64-1775): 0: 933: 19.94
+	Hs
		988821 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MYO5B_HUMAN (67-1775): 0: 925: 19.70
+	Hs
		1271065 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		MYO5A_HUMAN (64-1775): 0: 933: 19.94
+	Ce
		98435 CDC42_CAEEL (1-191): 2.47e-77: 231: 86.39		F0IWT2_CAEEL (1091-2040): 8.81e-99: 357: 20.33
+	Hs
		74011 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		MYO9A_HUMAN (591-2140): 3.81e-84: 311: 19.84
+	Hs
		74012 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		MYO9A_HUMAN (591-2140): 3.81e-84: 311: 19.84
+	Hs
		953688 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		MYO10_HUMAN (792-1023): 2.22e-34: 147: 35.44
+	Hs
		772724 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MYH9_HUMAN (947-1478): 1.78e-13: 78.7: 11.50
+	Hs
		772743 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		MYH9_HUMAN (947-1478): 1.78e-13: 78.7: 11.50