HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: OPTN (Q96CV9)
Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
Gene: OPTN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.744

The method score is based on:

Property Details
Experiments 11137014, 20634958, 20161783, 20085643, 23357852, 20388642, 22854040
Identification Methods two hybrid, pull down, affinity chromatography technology, bimolecular fluorescence complementation, confocal microscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0007030 - Golgi organization
and 1 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025