Interactor 1: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2
Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.60 | 0.578 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11387212 |
| Identification Methods | pull down, affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0010718 - positive regulation of epithelial to mesenchymal transition GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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| + | Dm |  |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
