HitPredict

Interactor 1: E5RI47 (E5RI47)
MAGUK p55 scaffold protein 2
Gene: MPP2

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	L27~L27, PDZ~PDZ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 197
+	Hs
		1122734 MPP2_HUMAN (1-189): 1.09e-74: 236: 84.93		LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00
+	Hs
		1122731 MPP2_HUMAN (1-189): 1.09e-74: 236: 84.93		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Hs
		1450016 PALS2_HUMAN (1-189): 9.36e-72: 227: 64.80		LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00
+	Hs
		95799 E5RI47_HUMAN (1-189): 2.99e-76: 228: 100.00		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Hs
		1437597 PALS2_HUMAN (1-189): 9.36e-72: 227: 64.80		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Hs
		167699 MPP2_HUMAN (1-189): 1.09e-74: 236: 84.93		LIN7A_HUMAN (6-194): 6.41e-51: 165: 80.42
+	Hs
		95789 E5RI47_HUMAN (1-189): 2.99e-76: 228: 100.00		LIN7A_HUMAN (6-194): 6.41e-51: 165: 80.42
+	Hs
		167723 PALS2_HUMAN (1-189): 9.36e-72: 227: 64.80		LIN7A_HUMAN (6-194): 6.41e-51: 165: 80.42
+	Hs
		168758 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		LIN7C_HUMAN (1-197): 1.56e-57: 181: 100.00
+	Hs
		168750 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Mm
		267259 CSKP_MOUSE (1-189): 5.43e-62: 208: 33.80		LIN7B_MOUSE (1-196): 1e-54: 174: 85.71
+	Hs
		167670 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		LIN7A_HUMAN (6-194): 6.41e-51: 165: 80.42
+	Mm
		1223777 MPP2_MOUSE (1-189): 9.94e-77: 241: 94.36		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		1091491 MPP2_HUMAN (1-189): 1.09e-74: 236: 84.93		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		168683 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		SNTB2_HUMAN (61-179): 3.01e-32: 123: 35.25
+	Hs
		168585 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		CSKP_HUMAN (13-194): 7.06e-31: 120: 20.53
+	Hs
		95791 E5RI47_HUMAN (1-189): 2.99e-76: 228: 100.00		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		168670 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Hs
		168680 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Hs
		168730 CSKP_HUMAN (1-189): 5.26e-62: 208: 33.80		DLG3_HUMAN (74-164): 8.63e-20: 88.3: 35.42