HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 649
+	Hs
		952855 ACTB_HUMAN (1-414): 0: 539: 35.66		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		993194 ACTG_HUMAN (1-414): 0: 538: 35.42		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		958217 ARP3_HUMAN (1-418): 0: 588: 100.00		DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98
+	Hs
		995623 ACTC_HUMAN (3-414): 0: 527: 35.59		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		977706 ACTA_HUMAN (3-414): 0: 526: 35.59		DREB_HUMAN (1-649): 3.27e-95: 308: 100.00
+	Hs
		953170 ACTB_HUMAN (1-414): 0: 539: 35.66		DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98
+	Hs
		995882 ACTC_HUMAN (3-414): 0: 527: 35.59		DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98
+	Ce
		534399 ACT2_CAEEL (3-414): 0: 536: 36.08		Q9XUT0_CAEEL (4-619): 3.41e-47: 178: 16.46
+	Hs
		952994 ACTB_HUMAN (1-414): 0: 539: 35.66		CTTB2_HUMAN (131-627): 2.71e-32: 136: 14.70
+	Sc
		587330 ACT_YEAST (1-414): 0: 528: 34.94		ABP1_YEAST (4-512): 1.46e-30: 128: 13.41
+	Hs
		958138 ARP3_HUMAN (1-418): 0: 588: 100.00		MICA3_HUMAN (205-646): 4.7e-10: 65.2: 9.90
+	Hs
		215916 ACTC_HUMAN (3-414): 0: 527: 35.59		SYNJ1_HUMAN (126-645): 3.15e-29: 126: 9.77
+	Hs
		958162 ARP3_HUMAN (1-418): 0: 588: 100.00		TITIN_HUMAN (184-598): 2.53e-09: 62.9: 10.29
+	Dm
		1014444 ACT6_DROME (3-414): 0: 530: 34.87		TITIN_DROME (173-542): 3.1e-27: 120: 13.80
+	Dm
		1014448 ACT6_DROME (3-414): 0: 530: 34.87		Q9VDF4_DROME (152-461): 2.5e-18: 91: 14.82
+	Dm
		56405 ACT6_DROME (3-414): 0: 530: 34.87		A1ZA72_DROME (119-643): 3.13e-17: 88.7: 8.97
+	Sc
		587320 ARP3_YEAST (6-417): 1.14e-171: 489: 58.35		ABP1_YEAST (4-512): 1.46e-30: 128: 13.41