HitPredict

Interactor 1: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Interactor 2: HFE (Q30201)
Hereditary hemochromatosis protein (HLA-H)
Gene: HFE

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 33961781, 20618438, 9546397, 15965644
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0009897 - external side of plasma membrane
GO:0033572 - transferrin transport
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 119
Hs

1 348
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Service provided by Combinatics, Japan

Last updated: 11Aug2025