Interactor 1: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1
Interactor 2: TFDP2 (Q14188)
Transcription factor Dp-2 (E2F dimerization partner 2)
Gene: TFDP2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9501179, 7739537, 35140242, 26186194, 28514442, 33961781, 9704927, 8755520, 34591642 |
| Identification Methods | affinity chromatography technology, pull down, comigration in non denaturing gel electrophoresis, two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DP~E2F_CC-MB, E2F_TDP~E2F_TDP |
| Common GO terms | GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
