HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: ITK (Q08881)
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)
Gene: ITK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8810341
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007165 - signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 620
+	Mm
		965993 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		ITK_MOUSE (1-620): 0: 764: 93.29
+	Hs
		440474 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		FYN_HUMAN (111-618): 0: 539: 33.40
+	Hs
		557198 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		SRC_HUMAN (95-618): 0: 535: 31.35
+	Hs
		473396 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		HCK_HUMAN (107-618): 1.07e-180: 523: 33.46
+	Mm
		683091 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		LYN_MOUSE (147-618): 3.25e-168: 491: 36.67
+	Hs
		463435 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		LYN_HUMAN (147-618): 1.44e-166: 487: 36.46
+	Hs
		834163 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		CSK_HUMAN (167-620): 1.98e-148: 438: 34.42
+	Hs
		463871 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LYN_HUMAN (147-618): 1.44e-166: 487: 36.46
+	Hs
		557318 PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17		SRC_HUMAN (95-618): 0: 535: 31.35
+	Hs
		557194 PCBP3_HUMAN (2-111): 7.55e-12: 68.5: 16.67		SRC_HUMAN (95-618): 0: 535: 31.35
+	Hs
		841010 PCBP1_HUMAN (7-111): 7.46e-12: 68.5: 14.95		FRK_HUMAN (144-619): 2.02e-168: 491: 33.47
+	Hs
		463706 FUBP3_HUMAN (336-457): 3.82e-12: 70.4: 24.59		LYN_HUMAN (147-618): 1.44e-166: 487: 36.46