HitPredict

Interactor 1: E9PQQ4 (E9PQQ4)
Heat shock protein family A (Hsp70) member 8
Gene: HSPA8

Interactor 2: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP70~TPR_11, HSP70~TPR_12, HSP70~TPR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 543
+	Hs
		536600 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00
+	Hs
		516183 HS71B_HUMAN (1-171): 5.22e-102: 307: 87.72		STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00
+	Hs
		731003 HS71L_HUMAN (2-171): 5.28e-101: 305: 84.71		STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00
+	Hs
		731123 HSP72_HUMAN (2-171): 7.24e-101: 304: 87.65		STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00
+	Dm
		538280 HSP7D_DROME (1-171): 2.62e-102: 308: 88.30		Q9VPN5_DROME (1-542): 1.57e-75: 249: 47.42
+	Hs
		537771 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		97163 E9PQQ4_HUMAN (1-171): 1.1e-108: 308: 100.00		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		516174 HS71A_HUMAN (1-171): 5.22e-102: 307: 87.72		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		516209 HS71B_HUMAN (1-171): 5.22e-102: 307: 87.72		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		1198774 Q53FA3_HUMAN (2-171): 4.79e-101: 305: 84.71		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		761494 HS71L_HUMAN (2-171): 5.28e-101: 305: 84.71		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		931079 HSP72_HUMAN (2-171): 7.24e-101: 304: 87.65		DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28
+	Hs
		761411 HS71L_HUMAN (2-171): 5.28e-101: 305: 84.71		TOM34_HUMAN (1-119): 8.16e-23: 100: 26.05
+	Dm
		538272 HSP7D_DROME (1-171): 2.62e-102: 308: 88.30		Q9VJD4_DROME (215-353): 5.38e-21: 96: 24.46
+	Hs
		185383 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		OGT1_HUMAN (5-241): 5.34e-17: 86.9: 12.24
+	Hs
		317978 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		TOM70_HUMAN (216-543): 8.73e-13: 73.1: 10.73
+	Mm
		989266 HSP7C_MOUSE (1-171): 4.23e-104: 313: 100.00		SGTA_MOUSE (202-327): 4.18e-10: 63.2: 33.33
+	Ce
		195270 HSP1_CAEEL (1-171): 1.59e-101: 306: 85.47		STIP1_CAEEL (356-535): 2.91e-12: 70: 17.11
+	Hs
		226689 HSP7C_HUMAN (1-171): 4.51e-104: 313: 100.00		SGTA_HUMAN (202-327): 4e-09: 60.1: 32.54
+	Hs
		930860 HSP72_HUMAN (2-171): 7.24e-101: 304: 87.65		SPAG1_HUMAN (405-527): 2.23e-10: 65.3: 14.63