HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	26496610, 27880917, 28330616, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 474
+	Hs
		915200 PP2AB_HUMAN (1-309): 0: 528: 97.41		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		890970 PP4C_HUMAN (4-309): 0: 508: 64.82		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		737825 PP1G_HUMAN (7-306): 0: 505: 45.96		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		931058 PP2AA_HUMAN (1-309): 0: 529: 100.00		MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57
+	Hs
		905891 PP1A_HUMAN (5-296): 0: 504: 46.51		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		724764 PP2AA_HUMAN (1-309): 0: 529: 100.00		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		930938 PP2AA_HUMAN (1-309): 0: 529: 100.00		CTTB2_HUMAN (2-204): 8.77e-10: 63.5: 11.82
+	Hs
		915248 PP2AB_HUMAN (1-309): 0: 528: 97.41		CTTB2_HUMAN (2-204): 8.77e-10: 63.5: 11.82
+	Hs
		725131 PP2AB_HUMAN (1-309): 0: 528: 97.41		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39
+	Hs
		724689 PP1G_HUMAN (7-306): 0: 505: 45.96		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		724746 PP1A_HUMAN (5-296): 0: 504: 46.51		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		906052 PP1A_HUMAN (5-296): 0: 504: 46.51		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		528366 PP1A_HUMAN (5-296): 0: 504: 46.51		MYH6_HUMAN (20-389): 4.46e-10: 64.2: 9.00
+	Hs
		148470 PP1G_HUMAN (7-306): 0: 505: 45.96		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		737818 PP1G_HUMAN (7-306): 0: 505: 45.96		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Mm
		906240 PP1A_MOUSE (5-296): 0: 504: 46.84		MYH6_MOUSE (28-399): 1.7e-09: 62.7: 11.05
+	Hs
		148613 PP1A_HUMAN (5-296): 0: 504: 46.51		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78