HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: MTMR4 (Q9NYA4)
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 (EC 3.1.3.95) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Myotubularin-related protein 4) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28675297, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019903 - protein phosphatase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1195
+	Hs
		971497 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MTMR3_HUMAN (1-1195): 0: 1014: 47.63
+	Hs
		971496 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MTMR2_HUMAN (7-608): 0: 714: 33.12
+	Hs
		331736 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MTMR5_HUMAN (161-716): 2.02e-135: 456: 22.97
+	Hs
		971972 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		MTMRC_HUMAN (6-550): 8.69e-131: 419: 18.87
+	Hs
		971683 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		FGD6_HUMAN (610-1195): 4.81e-77: 281: 14.80
+	Hs
		971677 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		FGD5_HUMAN (604-1191): 2.86e-72: 266: 14.73
+	Hs
		971915 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		RUFY1_HUMAN (974-1173): 7.34e-41: 163: 27.00