HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: FGD6 (Q6ZV73)
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
Gene: FGD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1430
+	Hs
		971677 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		FGD5_HUMAN (665-1430): 6.61e-132: 445: 37.92
+	Hs
		539991 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		BCR_HUMAN (339-1239): 2.64e-109: 378: 14.74
+	Hs
		971770 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		ARG28_HUMAN (408-1225): 1.46e-88: 320: 15.43
+	Mm
		972203 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		ARG28_MOUSE (309-1227): 4.42e-84: 306: 14.10
+	Hs
		971891 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		SPT13_HUMAN (684-1220): 1.95e-87: 301: 16.37
+	Hs
		972040 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		ARHG4_HUMAN (671-1242): 1.07e-86: 300: 15.60
+	Hs
		51063 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		PKHG3_HUMAN (810-1230): 2.93e-77: 282: 21.18
+	Hs
		971851 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		ARHG2_HUMAN (628-1214): 1.44e-77: 280: 14.43