HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0042826 - histone deacetylase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 1115
+	Mm
		972328 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		HDAC5_MOUSE (1-1115): 0: 769: 99.28
+	Hs
		972146 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC5_HUMAN (1-1115): 0: 742: 93.42
+	Hs
		940896 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC4_HUMAN (3-1095): 0: 677: 56.10
+	Hs
		972117 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC9_HUMAN (26-1048): 0: 629: 55.32
+	Hs
		971824 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC7_HUMAN (113-1115): 3.01e-162: 507: 39.96
+	Hs
		971492 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC1_HUMAN (666-1100): 2.28e-154: 470: 20.58
+	Mm
		972275 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		HDAC7_MOUSE (189-1115): 7.47e-142: 453: 37.67
+	Hs
		188231 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC3_HUMAN (673-1109): 1.01e-144: 443: 20.92
+	At
		871216 14310_ARATH (2-254): 2.4e-137: 388: 71.15		HDA5_ARATH (671-1112): 4.33e-146: 455: 33.26
+	Sc
		739854 BMH2_YEAST (4-242): 1.15e-134: 382: 77.08		RPD3_YEAST (664-1109): 2.9e-146: 447: 21.94
+	Sc
		709636 BMH1_YEAST (2-243): 2.44e-134: 381: 75.72		RPD3_YEAST (664-1109): 2.9e-146: 447: 21.94
+	Hs
		972093 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		HDAC6_HUMAN (611-1061): 1.42e-108: 369: 31.77