HitPredict

Interactor 1: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Interactor 2: NSUN2 (Q08J23)
RNA cytosine C(5)-methyltransferase NSUN2 (EC 2.1.1.-) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2) (Substrate of AIM1/Aurora kinase B) (mRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-) (tRNA cytosine C(5)-methyltransferase) (EC 2.1.1.-, EC 2.1.1.203) (tRNA methyltransferase 4 homolog) (hTrm4)
Gene: NSUN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, proximity-dependent biotin identification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1124 Hs			1 767
+	Hs
		674407 UFO_HUMAN (330-1106): 3.07e-162: 505: 23.47		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		665587 EPHB2_HUMAN (481-1115): 2.14e-157: 497: 21.39		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		609265 FGFR3_HUMAN (350-1118): 1.89e-157: 490: 24.44		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		507965 FGFR1_HUMAN (362-1124): 2.97e-155: 484: 23.82		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		445847 ROS1_HUMAN (448-1123): 1.09e-128: 437: 24.41		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		600561 EPHA1_HUMAN (525-1123): 4.19e-118: 390: 23.40		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		997549 MERTK_HUMAN (350-632): 2.4e-17: 89.7: 16.89		NSUN2_HUMAN (1-767): 0: 963: 100.00
+	Hs
		600525 EPHA1_HUMAN (525-1123): 4.19e-118: 390: 23.40		NOP2_HUMAN (22-533): 1.53e-126: 398: 20.04