HitPredict

Interactor 1: M2OM (Q02978)
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11)
Gene: SLC25A11

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	unassigned1853, 24725412
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 314 Hs			1 2527
+	Hs
		858269 TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		73279 B4E290_HUMAN (109-309): 1.73e-46: 164: 19.40		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3088 A0A0S2Z3G3_HUMAN (14-207): 1.02e-27: 111: 20.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1121048 Q53GR7_HUMAN (3-122): 4.54e-23: 101: 20.83		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1123866 Q59EI9_HUMAN (218-314): 9.89e-13: 69.5: 24.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130213 Q6NVC0_HUMAN (218-314): 2.08e-12: 68.7: 23.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3090 A0A0S2Z3H3_HUMAN (7-109): 1.71e-11: 65.6: 20.19		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518152 ADT1_HUMAN (7-109): 1.71e-11: 65.6: 20.19		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		518382 ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		397411 ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		397303 ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74