HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: ITSN2 (Q9NZM3)
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)
Gene: ITSN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22558309
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 7570 Hs			1 1697
+	Hs
		974083 DYST_HUMAN (1-7570): 0: 2600: 100.00		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		1059285 GOGB1_HUMAN (1119-1866): 1.3e-10: 71.3: 6.59		ITSN2_HUMAN (1-1697): 0: 969: 100.00
+	Hs
		963335 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		1045423 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		1078871 SYNE1_HUMAN (147-1832): 6.65e-10: 69: 8.83		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		224714 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		KALRN_HUMAN (187-1602): 9.25e-86: 315: 12.48
+	Hs
		1068677 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		ARHG4_HUMAN (1125-1592): 8.68e-73: 260: 18.41
+	Mm
		1142380 MACF1_MOUSE (260-1747): 3.42e-16: 89.8: 9.39		ARHG1_MOUSE (1199-1441): 2.78e-19: 97.1: 30.95
+	Hs
		809126 UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65		ARHGG_HUMAN (1196-1469): 3.19e-21: 102: 30.27
+	Mm
		57853 SPTB2_MOUSE (6042-7200): 1.95e-19: 100: 13.42		KALRN_MOUSE (216-869): 7.67e-09: 63.3: 8.32
+	Hs
		1068630 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		Q96D37_HUMAN (526-1189): 9.13e-14: 78.7: 13.15
+	Hs
		548710 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		VAV_HUMAN (526-1189): 1.23e-13: 78.3: 13.15
+	Mm
		57815 F6Q750_MOUSE (260-1747): 1.91e-16: 90.6: 9.39		KALRN_MOUSE (216-869): 7.67e-09: 63.3: 8.32
+	Mm
		57809 B9EKJ1_MOUSE (268-1534): 1.5e-10: 71.1: 11.78		KALRN_MOUSE (216-869): 7.67e-09: 63.3: 8.32
+	Mm
		57827 SPTN1_MOUSE (268-1534): 1.96e-10: 70.7: 11.75		KALRN_MOUSE (216-869): 7.67e-09: 63.3: 8.32
+	Mm
		57856 Q68FG2_MOUSE (257-1285): 4.95e-09: 65.9: 9.28		KALRN_MOUSE (216-869): 7.67e-09: 63.3: 8.32