HitPredict

Interactor 1: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Interactor 2: RPR1B (Q9NQG5)
Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)
Gene: RPRD1B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 326
+	Hs
		976135 RPB7_HUMAN (1-172): 1.49e-76: 227: 100.00		RPR1A_HUMAN (1-326): 1.48e-93: 282: 65.34
+	Hs
		976096 RPB7_HUMAN (1-172): 1.49e-76: 227: 100.00		RPRD2_HUMAN (9-322): 2.89e-73: 247: 25.00
+	Hs
		1447106 RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72		RPR1B_HUMAN (1-326): 7.02e-94: 283: 100.00
+	Hs
		1399384 RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72		RPR1A_HUMAN (1-326): 1.48e-93: 282: 65.34
+	Hs
		1217641 RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72		RPRD2_HUMAN (9-322): 2.89e-73: 247: 25.00
+	Hs
		326317 RPB7_HUMAN (1-172): 1.49e-76: 227: 100.00		SCAF4_HUMAN (8-187): 2.46e-36: 140: 17.46
+	Sp
		154263 RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42		SEB1_SCHPO (1-206): 1.59e-33: 132: 14.41
+	Sc
		757339 RPB7_YEAST (1-171): 4.47e-63: 193: 42.78		NRD1_YEAST (7-211): 9.81e-29: 118: 12.99