HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 346
+	Hs
		988278 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		961952 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		580990 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		1015367 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		466203 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		953392 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		955058 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		601238 RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		126547 RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914403 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914397 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914402 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914394 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914395 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		601218 RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		914238 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		EFNA4_HUMAN (13-211): 5.62e-53: 175: 23.42