HitPredict

Interactor 1: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	15045029, 26831523, 14645854, 16299513, 17289584, 19106085, 37968396, 21179020
Identification Methods	tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 463 Sc			1 134
+	Sc
		392191 RUVB1_YEAST (1-463): 0: 682: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392553 RUVB1_YEAST (1-463): 0: 682: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sp
		815623 RUVB1_SCHPO (1-463): 0: 676: 70.41		H2AZ_SCHPO (18-130): 1.98e-47: 151: 73.45
+	Hs
		470209 RUVB1_HUMAN (2-461): 0: 682: 67.61		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Dm
		446324 RUVB1_DROME (15-461): 0: 648: 66.89		H2AV_DROME (10-129): 3.97e-52: 163: 69.67
+	Hs
		1216283 RUVB2_HUMAN (1-458): 0: 637: 41.09		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1151396 RUVB2_HUMAN (1-458): 0: 637: 41.09		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Sc
		1015643 RUVB2_YEAST (15-463): 0: 622: 41.15		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392228 RUVB2_YEAST (15-463): 0: 622: 41.15		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sp
		294002 RUVB2_SCHPO (16-463): 0: 632: 42.35		H2AZ_SCHPO (18-130): 1.98e-47: 151: 73.45
+	Sc
		392614 RUVB2_YEAST (15-463): 0: 622: 41.15		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		470207 RUVB2_HUMAN (1-458): 0: 637: 41.09		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		1175321 RUVB2_HUMAN (1-458): 0: 637: 41.09		H2AV_HUMAN (10-134): 1.67e-40: 133: 67.72