HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: FEV (Q99581)
Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
Gene: FEV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 773 Hs			1 238
+	Hs
		980640 TLE1_HUMAN (8-773): 0: 580: 86.27		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		980853 TLE3_HUMAN (8-773): 0: 539: 80.90		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		507403 TLE1_HUMAN (8-773): 0: 580: 86.27		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		507404 TLE3_HUMAN (8-773): 0: 539: 80.90		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		794534 TLE1_HUMAN (8-773): 0: 580: 86.27		ETV4_HUMAN (36-186): 3.64e-46: 161: 39.74
+	Hs
		785356 TLE1_HUMAN (8-773): 0: 580: 86.27		ELK3_HUMAN (61-215): 1.5e-41: 147: 29.68
+	Hs
		542002 TLE3_HUMAN (8-773): 0: 539: 80.90		ETS1_HUMAN (8-151): 2.42e-54: 182: 46.31
+	Dm
		558359 GROU_DROME (8-773): 1.23e-144: 443: 59.14		ETS3_DROME (20-223): 3.68e-56: 188: 48.83
+	Hs
		993566 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		507408 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Ce
		106121 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		G5EDL0_CAEEL (47-216): 4.95e-48: 165: 33.92
+	Hs
		840370 TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68		ERF_HUMAN (24-183): 1.94e-46: 163: 41.25
+	Ce
		136467 UNC37_CAEEL (24-773): 5.04e-95: 310: 36.86		ETS7_CAEEL (36-233): 6.35e-41: 141: 22.82
+	Hs
		245579 TBL1X_HUMAN (572-772): 8.38e-46: 174: 15.60		ERF_HUMAN (24-183): 1.94e-46: 163: 41.25
+	Hs
		781217 TBL1Y_HUMAN (572-772): 1.73e-44: 169: 15.60		ETV3_HUMAN (30-193): 7.5e-48: 166: 39.39
+	Hs
		840410 TBL1Y_HUMAN (572-772): 1.73e-44: 169: 15.60		ERF_HUMAN (24-183): 1.94e-46: 163: 41.25
+	Hs
		692171 SNR40_HUMAN (510-690): 4.15e-10: 64.3: 27.98		ELF1_HUMAN (4-230): 1.52e-58: 197: 23.61
+	Hs
		840414 TBL1R_HUMAN (651-770): 4.06e-20: 96.4: 13.24		ERF_HUMAN (24-183): 1.94e-46: 163: 41.25