HitPredict

Interactor 1: ARPC3 (Q05933)
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Gene: ARC18

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	18467557, 37968396, 29386393, 21035341
Identification Methods	protein complementation assay, affinity chromatography technology, pull down, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030833 - regulation of actin filament polymerization GO:0045010 - actin nucleation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 178 Sc			1 633
+	Hs
		126882 ARPC3_HUMAN (1-178): 4.24e-97: 280: 46.07		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Mm
		936476 ARPC3_MOUSE (1-178): 1.34e-97: 281: 46.63		WASP_MOUSE (3-386): 3.86e-37: 147: 18.37
+	Hs
		169044 ARPC3_HUMAN (1-178): 4.24e-97: 280: 46.07		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Sp
		193733 ARPC3_SCHPO (1-178): 2.32e-89: 260: 53.63		WSP1_SCHPO (4-416): 3.99e-22: 102: 22.03