HitPredict

Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pro_isomerase~Ras
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 236
+	Hs
		986521 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		986323 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		981381 PPIE_HUMAN (2-163): 2.09e-88: 262: 67.28		RAB1A_HUMAN (22-234): 7.35e-76: 229: 21.10
+	Hs
		953381 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		580976 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		719422 PPIF_HUMAN (3-164): 6.29e-92: 267: 76.54		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		961931 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		962637 PPIE_HUMAN (2-163): 2.09e-88: 262: 67.28		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		986341 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		955034 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		986722 PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00		RHOJ_HUMAN (32-214): 8.34e-59: 186: 50.27