HitPredict

Interactor 1: YSH1 (Q06224)
Endoribonuclease YSH1 (EC 3.1.27.-) (Yeast 73 kDa homolog 1) (mRNA 3'-end-processing protein YSH1)
Gene: YSH1

Interactor 2: CFT1 (Q06632)
Protein CFT1 (Cleavage factor two protein 1)
Gene: CFT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	11805826, 10523662, 16429126, 37968396, 16554755
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0006369 - termination of RNA polymerase II transcription GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 779 Sc			1 1357
+	At
		1320907 CPSF3_ARATH (4-778): 0: 655: 37.76		CPSF1_ARATH (2-1347): 0: 894: 15.45
+	Sc
		988501 CFT2_YEAST (15-546): 2.92e-90: 304: 14.74		CFT1_YEAST (1-1357): 0: 1208: 100.00
+	Sp
		142956 YSH1_SCHPO (2-778): 0: 629: 47.11		CFT1_SCHPO (13-1350): 0: 868: 23.47
+	Hs
		1014217 CPSF3_HUMAN (1-778): 0: 694: 37.21		CPSF1_HUMAN (2-1347): 0: 791: 17.37
+	At
		1208877 CPS3B_ARATH (9-528): 1.23e-153: 463: 28.27		CPSF1_ARATH (2-1347): 0: 894: 15.45
+	At
		1323026 CPSF2_ARATH (6-446): 4.23e-121: 382: 23.83		CPSF1_ARATH (2-1347): 0: 894: 15.45
+	Hs
		1014211 CPSF2_HUMAN (6-729): 5.19e-127: 399: 18.13		CPSF1_HUMAN (2-1347): 0: 791: 17.37
+	Sp
		251783 CFT2_SCHPO (26-546): 1.02e-86: 293: 18.00		CFT1_SCHPO (13-1350): 0: 868: 23.47