HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: LTBP4 (Q8N2S1)
Latent-transforming growth factor beta-binding protein 4 (LTBP-4)
Gene: LTBP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1624
+	Hs
		857404 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		580920 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		857560 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		857395 RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		857396 CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		857413 RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		857398 RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98		NOTC1_HUMAN (502-1624): 2.77e-97: 351: 16.29
+	Hs
		988304 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Hs
		581005 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Hs
		1047734 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Hs
		988749 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		LTBP3_HUMAN (24-794): 1.88e-27: 124: 17.80
+	Hs
		953406 RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Hs
		955084 CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Hs
		1015385 RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35		NOTC2_HUMAN (1-717): 1.51e-32: 140: 13.42
+	Mm
		988903 RAC1_MOUSE (1-192): 4.32e-85: 250: 100.00		LTBP1_MOUSE (23-796): 4.6e-24: 112: 15.60
+	Hs
		988269 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		JAG1_HUMAN (1191-1622): 1.53e-23: 110: 10.78
+	Hs
		580983 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		JAG1_HUMAN (1191-1622): 1.53e-23: 110: 10.78
+	Hs
		1008026 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		JAG1_HUMAN (1191-1622): 1.53e-23: 110: 10.78
+	Hs
		953388 RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19		JAG1_HUMAN (1191-1622): 1.53e-23: 110: 10.78
+	Hs
		1008013 RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35		JAG1_HUMAN (1191-1622): 1.53e-23: 110: 10.78