HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: UBAP2 (Q5T6F2)
Ubiquitin-associated protein 2 (UBAP-2) (RNA polymerase II degradation factor UBAP2)
Gene: UBAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	29395067, unassigned1973
Identification Methods	proximity labelling technology, two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005694 - chromosome GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 632 Hs			1 1119
+	Mm
		729575 FMR1_MOUSE (1-632): 0: 1063: 93.99		UBAP2_MOUSE (1-1119): 7.04e-107: 363: 77.78
+	Hs
		988873 FMR1_HUMAN (1-632): 0: 1106: 100.00		UBP2L_HUMAN (1-1119): 1.83e-54: 209: 39.07
+	Mm
		729538 FMR1_MOUSE (1-632): 0: 1063: 93.99		UBP2L_MOUSE (1-1119): 1.29e-56: 216: 38.95
+	Hs
		989097 FMR1_HUMAN (1-632): 0: 1106: 100.00		CECR2_HUMAN (294-1097): 1.16e-20: 100: 11.98
+	Mm
		729419 FMR1_MOUSE (1-632): 0: 1063: 93.99		ZO1_MOUSE (372-1089): 6.95e-27: 121: 12.00
+	Hs
		257605 FMR1_HUMAN (1-632): 0: 1106: 100.00		ANR17_HUMAN (423-1113): 1.88e-12: 74.1: 12.71
+	Mm
		729583 FMR1_MOUSE (1-632): 0: 1063: 93.99		ANR17_MOUSE (188-934): 3e-10: 66.9: 9.96
+	Mm
		1207078 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		UBAP2_MOUSE (1-1119): 7.04e-107: 363: 77.78
+	Hs
		843723 FXR1_HUMAN (1-334): 0: 604: 73.95		UBAP2_HUMAN (1-1119): 5.13e-116: 388: 100.00
+	Mm
		1142889 FXR1_MOUSE (1-334): 0: 596: 73.65		UBAP2_MOUSE (1-1119): 7.04e-107: 363: 77.78
+	Mm
		1194420 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		UBP2L_MOUSE (1-1119): 1.29e-56: 216: 38.95
+	Hs
		843668 FXR1_HUMAN (1-334): 0: 604: 73.95		UBP2L_HUMAN (1-1119): 1.83e-54: 209: 39.07
+	Mm
		1142859 FXR1_MOUSE (1-334): 0: 596: 73.65		UBP2L_MOUSE (1-1119): 1.29e-56: 216: 38.95
+	Mm
		761861 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		ZO1_MOUSE (372-1089): 6.95e-27: 121: 12.00
+	Mm
		1207085 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		ANR17_MOUSE (188-934): 3e-10: 66.9: 9.96
+	Hs
		843883 FXR1_HUMAN (1-334): 0: 604: 73.95		CECR2_HUMAN (294-1097): 1.16e-20: 100: 11.98
+	Mm
		1142857 FXR1_MOUSE (1-334): 0: 596: 73.65		Q80U83_MOUSE (792-1075): 2.88e-16: 86.4: 15.93
+	Hs
		257587 FXR1_HUMAN (1-334): 0: 604: 73.95		ANR17_HUMAN (423-1113): 1.88e-12: 74.1: 12.71
+	Hs
		843899 FXR1_HUMAN (1-334): 0: 604: 73.95		TARA_HUMAN (119-959): 9.63e-11: 68.5: 7.37
+	Mm
		102653 FXR1_MOUSE (1-334): 0: 596: 73.65		G3X972_MOUSE (695-1086): 8.17e-09: 62.3: 10.51