HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.718

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442, 15161933
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1253
+	Hs
		990432 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PHLB1_HUMAN (21-1252): 2.41e-60: 229: 27.39
+	Hs
		340105 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PCNT_HUMAN (193-1114): 4.52e-50: 197: 16.74
+	Mm
		989976 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		MYH10_MOUSE (212-1125): 9.94e-33: 140: 9.33
+	Hs
		773148 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		MYH10_HUMAN (212-1125): 7.51e-33: 141: 9.11
+	Hs
		990855 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH2_HUMAN (215-1078): 3.02e-29: 129: 9.06
+	Hs
		776800 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH11_HUMAN (177-1016): 1.79e-26: 120: 8.69
+	Hs
		776794 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		MYH11_HUMAN (177-1016): 1.79e-26: 120: 8.69
+	Hs
		772728 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH9_HUMAN (468-1188): 3.76e-24: 112: 9.27
+	Hs
		556912 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH7_HUMAN (195-988): 2.8e-23: 110: 8.71
+	Hs
		319061 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (42-1075): 8.56e-20: 98.6: 9.42
+	Hs
		319058 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		K0754_HUMAN (42-1075): 8.56e-20: 98.6: 9.42
+	Mm
		990062 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		PLEC_MOUSE (370-1115): 4.6e-15: 83.3: 10.64
+	Mm
		990059 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		MY18A_MOUSE (415-1127): 2.04e-10: 67.7: 16.06
+	Hs
		990678 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (570-1223): 1.25e-10: 68.5: 9.70
+	Hs
		990250 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (379-991): 2e-10: 67.8: 12.17
+	Hs
		587614 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DESP_HUMAN (412-840): 2.67e-10: 67.3: 19.03
+	Mm
		98050 1433E_MOUSE (2-241): 9.95e-144: 403: 68.18		DESP_MOUSE (362-840): 9.47e-11: 68.8: 18.73
+	Mm
		990028 1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59		MYH9_MOUSE (138-631): 1.83e-09: 64.6: 11.09
+	Hs
		990214 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DCTN1_HUMAN (447-912): 5.78e-10: 66.1: 15.78
+	Hs
		990856 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH13_HUMAN (541-1107): 4.66e-09: 63.4: 15.67